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Two drugs shown to prolong survival in advanced melanoma cases

Two drugs shown to prolong survival in advanced melanoma cases

Two new drugs prolong the lives of patients with advanced melanoma, one of the deadliest forms of skin cancer and one that is notoriously difficult to treat, let alone cure.

The first treatment, vemurafenib, inhibits a gene mutation harbored in half of all melanoma patients, but is not yet approved by the U.S. Food and Drug Administration. The other drug, Yervoy (ipilumumab), is an immune system therapy that won approval in March.

Research on both drugs was presented Sunday at the annual meeting of the American Society of Clinical Oncology in Chicago while also being published simultaneously online in the New England Journal of Medicine.

Free outdoor exercise facilities near Ft. Payne

Free outdoor exercise facilities near Ft. Payne

If you like to get into shape for the summer, just drive a few miles down the road and head to Mentone.

Scientists discover "ultra-bad" cholesterol

Scientists discover "ultra-bad" cholesterol

 A new, "ultra-bad" form of low-density lipoprotein (LDL) cholesterol has been discovered in people with a high risk for heart disease, according to British researchers.

They found that the cholesterol, called MGmin-LDL, is super-sticky, making it more likely to attach to the walls of arteries and form fatty plaques, which could lead to heart attacks and stroke.

The discovery provides a possible explanation for the increased risk of coronary heart disease in diabetics and could help researchers develop new anti-cholesterol treatments, the researchers suggested.

Have a safe barbeque this Memorial Day

Have a safe barbeque this Memorial Day

As grills around the country are fired up for Memorial Day, one food safety expert has advice on how to ensure your barbeque or picnic is not only fun but safe.

Nancy Donely, founder of STOP Foodborne Illness and a leading national advocate for food safety, urges people to take the following safety precautions when cooking and eating outdoors this summer:

Antidepressants work overall, but some symptoms may persist

Antidepressants work overall, but some symptoms may persist

Antidepressants may not improve all symptoms of depression, according to a new study.

Researchers analyzed data from a U.S. National Institute of Mental Health-sponsored study of depression treatment, which involved more than 4,000 people with major depression around the country and is the largest study on depression treatment to date.

While antidepressant medications worked in general, all patients taking them reported three to 13 residual symptoms, and 75 percent reported five or more residual symptoms.

These symptoms included insomnia that occurs in the middle of the night (79 percent); sadness (nearly 71 percent), and problems with concentration and decision-making (nearly 70 percent), said the researchers at UT Southwestern Medical Center in Dallas.

Scientists find molecular similarities in brains of those with autism

Scientists find molecular similarities in brains of those with autism

The symptoms and severity of autism vary widely, but new research shows remarkable similarities at the molecular level in the brains of people with the disorder.

Researchers from Los Angeles, Toronto and London analyzed post-mortem brain tissue samples from 19 people with autism and 17 without.

In the healthy brains, researchers saw distinct differences in the gene expression in the frontal lobe vs. the temporal lobe of the cerebral cortex -- differences that help determine the structure and function of the two brain regions.

Could "extreme" low-cal diets bring longer, healthier life?

Could "extreme" low-cal diets bring longer, healthier life?

Science has shown that diets that veer close to starvation can make everything from mice to monkeys live longer.

But can such a strict eating regimen prolong human lives, and if so, would those extra years be healthy, happy ones?

Recent research from Washington University scientists found that people who slashed their calorie intake have lower core body temperatures than those who eat more. Core body temperature is the temperature at which all of the functions in the body can operate at maximum efficiency, so the link looks like a positive one, according to some researchers.

Trent Arsenault, a 35-year-old engineer in the Bay Area, certainly hopes so.